TechValidate Research on QIAGEN Bioinformatics

These pages present data that TechValidate has sourced via direct research with verified customers and users of QIAGEN Bioinformatics. TechValidate stands behind the authenticity of all published data. Learn more »



2,779 Customers Surveyed

19,584 Data Points Collected

260 Published TechFacts

29 Published Charts

23 Published Case Studies



Featured Research Collections for QIAGEN Bioinformatics

Curated collections and slideshows of TechValidate research data on QIAGEN Bioinformatics.



Selected Research Highlights


QIAGEN Bioinformatics Customer Review

Gold Standard in Inherited Interpretation

5/5 Stars

Please share details on your experience with it.

HGMD is my gold standard for variant analysis.

Would you recommend our software to others, and if so, why?

Yes, I’ve found no errors thus far.

CLC Genomics Workbench Customer Review

5/5 Stars

What features or capabilities did you like the most in the software?

Creating metadata, comparing samples, checking for known variants in read mapping results.

Case Study: Non Profit Research Institute and Ingenuity Variant Analysis for Ion Reporter

Introduction

This case study of a non-profit is based on a April 2014 survey of Ingenuity Variant Analysis plugin for Ion Reporter customers by TechValidate, a 3rd-party research service. The profiled organization asked to have their name blinded to protect their confidentiality.

“We can simply output the annotated variant list with AA, Nuc, MAF etc making it easy to get to your variants of interest without any expertise needed.”

Challenges

  • Tried the Ingenuity Variant Analysis plugin for Ion Reporter because of easy to access within Ion Reporter.
  • Addresses the following challenges in Ion Reporter:
    • additional annotation

Use Case

  • Has 2-5 people in their lab using the Ingenuity Variant Analysis Plugin for Ion Reporter.
  • Is using for Gene Panel sample types.

Results

  • Achieved the following with the Ingenuity Variant Analysis plugin for Ion Reporter:
    • Helped reduce time to generate a short list of interesting variants
    • Increased efficiency and team productivity
  • Received the following scientific benefits:
    • Performed causal network analysis to identify relevant variants in genes
    • Quickly identified new findings
  • The following differentiates from competitive products:
    • Speed of access to application
    • Flexibility
    • Ability to customize analysis

Case Study: Educational Institution

Introduction

This case study of a educational institution is based on a July 2013 survey of Ingenuity IPA customers by TechValidate, a 3rd-party research service. The profiled organization asked to have their name blinded to protect their confidentiality.

“I appreciate the insight from IPA analysis, especially from upstream regulator analysis.”

Challenges

  • Solved the following challenges since deploying IPA for RNA sequencing analysis:
    • Can now distinguish different isoforms
  • Purchased IPA for RNA sequencing analysis for the following reasons:
    • Interpret the impact of expression changes in the context of biological processes, disease and cellular phenotypes, and molecular interactions
    • Compile targeted bibliographies with experimental evidence linking their differentially expressed isoforms to biological processes, disease, and molecular interactions

Use Case

  • Uses the following species in their RNA seq analysis:
    • Humans
    • Mice
  • Uses the following upstream analysis packages to generate RNA-Seq expression values:
    • Use R and perl

Results

  • Purchased IPA for RNA seq analysis over the following competitors:
    • In-house developed software
  • Rates the following IPA capabilities compared to the competition:
    • Faster time to insights: highly differentiated
    • Ease of use: differentiated
    • Novel insights: highly differentiated
    • Deeper analysis: highly differentiated
  • Saved 1 to 3 days per analysis with IPA for their RNA seq analysis.
  • Is very satisfied with the value for identifying biologically relevant isoforms from RNA seq data using IPA.
  • Increased the productivity of their bioinformatics staff for RNA seq analysis by 2 to 5x with IPA.

Ingenuity Variant Analysis compared with other platforms

Rate the following Ingenuity Variant Analysis capabilities in terms of how differentiated they are compared to other data analysis solutions you have used.

5 (Strongly differentiated) 4 (Very differentiated) 3 (Differentiated) 2 (Somewhat differentiated) 1 (Not differentiated)

Accessible / Easy to use
Sharing with colleagues/peers
Fast
Accurate evidence
Secure

Ingenuity Variant Analysis used for both Gene Panel and Exome/Genome in Ion Reporter

For which sample types are you using the Ingenuity Variant Analysis plugin for Ion Reporter?

Gene Panel
62%
Exome / Genome
14%
Both Gene Panel and Exome/Genome
24%


More to Explore



About QIAGEN Bioinformatics

QIAGEN offers industry-leading applications for the analysis, interpretation, and reporting of biological data. Understanding raw data is one of the most significant challenges in modern molecular methods. Data must be examined within the context of complex biological processes, and rapidly increasing throughput makes analyses time and labor intensive. QIAGEN’s portfolio of powerful tools addresses this bottleneck with innovative applications based on cutting-edge bioinformatics.

QIAGEN Bioinformatics Website   QIAGEN Website