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TechValidate Research on QIAGEN Bioinformatics

These pages present data that TechValidate has sourced via direct research with verified customers and users of QIAGEN Bioinformatics. TechValidate stands behind the authenticity of all published data. Learn more »



645 Customers Surveyed

5,057 Data Points Collected

82 Published TechFacts

22 Published Charts

22 Published Case Studies



Selected Research Highlights


Ingenuity Variant Analysis compared with other platforms

Rate the following Ingenuity Variant Analysis capabilities in terms of how differentiated they are compared to other data analysis solutions you have used.

S 5 (Strongly differentiated) S 4 (Very differentiated) S 3 (Differentiated) S 2 (Somewhat differentiated) S 1 (Not differentiated)

Accessible / Easy to use
Sharing with colleagues/peers
Fast
Accurate evidence
Secure

Case Study: Semmelweis University

Introduction

This case study of Semmelweis University is based on a July 2013 survey of Ingenuity IPA customers by TechValidate, a 3rd-party research service.

“[IPA provides] complex, integrated analysis, pathway analysis, and super visualization.”

Challenges

  • Solved the following challenges since deploying IPA for RNA sequencing analysis:
    • Improved understanding of the structure of different isoforms
    • Improved precise measurement of transcripts
    • Can now distinguish different isoforms
    • Can more clearly identify biologically relevant isoforms
  • Purchased IPA for RNA sequencing analysis for the following reasons:
    • Interpret the impact of expression changes in the context of biological processes, disease and cellular phenotypes, and molecular interactions

Use Case

  • Uses the following species in their RNA seq analysis:
    • Humans
  • Uses the following upstream analysis packages to generate RNA-Seq expression values:
    • CLC bio

Results

  • Purchased IPA for RNA seq analysis over the following competitors:
    • In-house developed software
    • CLC Genomic Workbench
  • Rates the following IPA capabilities compared to the competition:
    • Faster time to insights: differentiated
    • Ease of use: differentiated

Qiagen Bioinformatics Commercial Solutions Customer Testimonial

The ready made solutions save time and provide opportunities to analyze NGS data with limited bio-information knowledge.

Laura Lahtinen, Primary Investigator, Central Finland Health Care District

Qiagen Bioinformatics Commercial Solutions Customer Testimonial

All in One Solution for your Analytical Needs

Beginning to end pipeline.

Professor, Educational Institution

Top Drivers for Selecting IPA for RNA-seq Analysis over In-House Developed Software

What were the top drivers for selecting IPA for RNA seq analysis?

Quickly identify differentially expressed isoforms
33%
Interpret the impact of expression changes in the context of biological processes, disease and cellular phenotypes, and molecular interactions
71%
Visualize your RNA seq data in the context of Isoform View
21%
Compile targeted bibliographies with experimental evidence linking your differentially expressed isoforms to biological processes, disease, and molecular interactions
33%
Other
4%

Case Study: Academic Research Institution and Ingenuity Variant Analysis

Introduction

This case study of a educational institution is based on a March 2013 survey of Ingenuity Systems customers by TechValidate, a 3rd-party research service. The profiled organization asked to have their name blinded to protect their confidentiality.

“Through the use of Ingenuity we are now able to quickly and efficiently analyze our data and share the results with our collaborators.”

Challenges

  • Solved the following challenges by deploying Ingenuity Variant Analysis:
    • Realized faster and easier identification of causal variants
    • Reduced the need for developing own informatics pipeline
    • Enabled support for more studies by providing a self-service tool for colleagues and collaborators
  • Purchased Ingenuity Variant Analysis for the following reasons:
    • Reduce time to identify variants worth following up on
    • Identify high impact, most compelling variants to follow up on
    • Access user friendly interface and no bioinformatics experience needed
    • Collaborate and share easily with colleagues and peers

Use Case

  • Uses the following applications with Ingenuity Variant Analysis:
    • DNA sequencing – Whole Exome
    • DNA sequencing – Targeted / Gene Panel
  • Sequencing data is from the following platforms:
    • Illumina Genome Analyzer (GA) / HiSeq
    • Life Technologies SOLiD

Results

  • Chose Ingenuity Systems over the following solutions:
    • In-house developed software
  • Saves 1 to 3 days per sample using Ingenuity Variant Analysis for DNA variant annotation and analysis.
  • Rated the following Ingenuity Variant Analysis capabilities in terms of how differentiated they are compared to other data analysis solutions:
    • Speed: 3 (differentiated)
    • Accessibility/ ease of use: 4 (very differentiated)
    • Sharing with colleagues/peers: 5 (strongly differentiated)
    • Security: 4 (very differentiated)
  • Is satisfied with the ease of use of Ingenuity Variant Analysis.


More to Explore



About QIAGEN Bioinformatics

QIAGEN offers industry-leading applications for the analysis, interpretation, and reporting of biological data. Understanding raw data is one of the most significant challenges in modern molecular methods. Data must be examined within the context of complex biological processes, and rapidly increasing throughput makes analyses time and labor intensive. QIAGEN’s portfolio of powerful tools addresses this bottleneck with innovative applications based on cutting-edge bioinformatics.

QIAGEN Bioinformatics Website   QIAGEN Website