TechValidate Research on Thermo Fisher Scientific Molecular Biology

3 Case Studies


Thermo Fisher Products and Services Case Study

Small Business Health Care Company

Introduction

This case study of a small business health care company is based on a June 2019 survey of Thermo Fisher Products and Services customers by TechValidate, a 3rd-party research service. The profiled company asked to have their name blinded to protect their confidentiality.

“It has been very useful for stabilising the assay without a need to concentrate the enzyme in an effort to minimise glycerol level.”
- R&D Manager

Challenges

The business challenges that led the profiled company to evaluate and ultimately select Thermo Fisher Products and Services:

  • Challenges they were experiencing with their previous supplier(s) that prompted them to evaluate Thermo Fisher Lyo-ready enzymes:
    • Performance variability

Use Case

The key features and functionalities of Thermo Fisher Products and Services that the surveyed company uses:

  • Thermo Fisher Lyo-ready enzyme(s) for which they have included in their molecular assay:
    • Lyo-ready Maxima reverse transcriptase
    • Ribolock
  • Chose Thermo Fisher Lyo-ready enzymes for their molecular diagnostics kits for the following reasons:
    • Better performance with Thermo Fisher Lyo-ready enzymes than other commercially available suppliers
    • Compatibility with our assay design and platform
    • Proactive rather than reactive partnership (e.g., support, troubleshooting, consulting, etc.)
  • Applications for which they already use Thermo Fisher Lyo-ready enzymes:
    • Isothermal Lamp BART assay

Results

The surveyed company achieved the following results with Thermo Fisher Products and Services:

  • Improvements they have achieved using Thermo Fisher Lyo-ready enzymes in their assay development:
    • Robust amplification of challenging templates (e.g., low-purity, degraded)
    • Increased sensitivity/yield
    • Reproducible assay with batch-to-batch consistency
    • Easy to lyophilize
  • Thermo Fisher capabilities compared to other suppliers evaluated or used for lyophilization-compatible enzymes:
    • Ease of adoption for lyophilization in assay development: best in class
    • Breadth of product portfolio and customization capabilities: significantly better
    • Dedicated and responsive customer/technical support: best in class
    • Scalability to support your future commercialization needs: significantly better
    • Overall performance from lyophilization-compatible enzyme(s): best in class

Thermo Fisher Products and Services Case Study

Small Business Consumer Products Company

Introduction

This case study of a small business consumer products company is based on a June 2019 survey of Thermo Fisher Products and Services customers by TechValidate, a 3rd-party research service. The profiled company asked to have their name blinded to protect their confidentiality.

“Thermo Fisher Lyo-ready enzymes deliver comparable performances as glycerol containing enzymes, enabling consistent and reproducible molecular diagnostic assays.”

“They have performed better than other enzymes, this has allowed us more robust amplification. " – R&D Director

Challenges

The business challenges that led the profiled company to evaluate and ultimately select Thermo Fisher Products and Services:

  • Challenges they were experiencing with their previous supplier(s) that prompted them to evaluate Thermo Fisher Lyo-ready enzymes:
    • Nothing, Thermo enzyme works better than the competitor.

Use Case

The key features and functionalities of Thermo Fisher Products and Services that the surveyed company uses:

  • Thermo Fisher Lyo-ready enzyme(s) for which they have included in their molecular assay:
    • Bsm Polymerase
  • Chose Thermo Fisher Lyo-ready enzymes for their molecular diagnostics kits for the following reasons:
    • Better performance with Thermo Fisher Lyo-ready enzymes than other commercially available suppliers
  • Applications for which they already use Thermo Fisher Lyo-ready enzymes:
    • None

Results

The surveyed company achieved the following results with Thermo Fisher Products and Services:

  • Improvements they have achieved using Thermo Fisher Lyo-ready enzymes in their assay development:
    • Robust amplification of challenging templates (e.g., low-purity, degraded)
  • Thermo Fisher capabilities compared to other suppliers evaluated or used for lyophilization-compatible enzymes:
    • Ease of adoption for lyophilization in assay development: worse
    • Breadth of product portfolio and customization capabilities: better
    • Dedicated and responsive customer/technical support: better
    • Scalability to support your future commercialization needs: worse
    • Overall performance from lyophilization-compatible enzyme(s): better

Thermo Fisher Products and Services Case Study

Medium Enterprise Health Care Company

Introduction

This case study of a medium enterprise health care company is based on a May 2019 survey of Thermo Fisher Products and Services customers by TechValidate, a 3rd-party research service. The profiled company asked to have their name blinded to protect their confidentiality.

“Providing robust glycerol-free enzymes that performed in our assays as required without the need for big changes in formulations/ processes. Providing reliable technical support and flexible supply service.”
- R&D Manager

Challenges

The business challenges that led the profiled company to evaluate and ultimately select Thermo Fisher Products and Services:

  • Challenges they were experiencing with their previous supplier(s) that prompted them to evaluate Thermo Fisher Lyo-ready enzymes:
    • Difficulty integrating lyophilization-compatible enzymes into existing protocol

Use Case

The key features and functionalities of Thermo Fisher Products and Services that the surveyed company uses:

  • Thermo Fisher Lyo-ready enzyme(s) for which they have included in their molecular assay:
    • Lyo-ready Platinum Taq DNA polymerase
  • Chose Thermo Fisher Lyo-ready enzymes for their molecular diagnostics kits for the following reasons:
    • Large selection of enzyme options for reverse transcriptases and DNA polymerases
    • Compatibility with our assay design and platform
    • Proactive rather than reactive partnership (e.g., support, troubleshooting, consulting, etc.)
  • Applications for which they already use Thermo Fisher Lyo-ready enzymes:
    • RT-qPCR/qPCR assay
    • Multiplex PCR

Results

The surveyed company achieved the following results with Thermo Fisher Products and Services:

  • Improvements they have achieved using Thermo Fisher Lyo-ready enzymes in their assay development:
    • Robust amplification of challenging templates (e.g., low-purity, degraded)
    • Increased sensitivity/yield
    • Reproducible assay with batch-to-batch consistency
    • Minimal optimization
  • Thermo Fisher capabilities compared to other suppliers evaluated or used for lyophilization-compatible enzymes:
    • Breadth of product portfolio and customization capabilities: significantly better
    • Dedicated and responsive customer/technical support: significantly better
    • Scalability to support your future commercialization needs: significantly better



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